Gene: PIK3CA ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419

2004
dbSNP: rs121913273
rs121913273
PIK3CA
C 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058

2010
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058

2010
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058

2010
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058

2010
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058

2010
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589

2012
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589

2012
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589

2012
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589

2012